SBRI Stem-cell and Brain Research Institute - France (Lyon)

Lab News

                                                                                             2017

  • Sept. 2017. The Heinrich lab is moving to SBRI in Lyon

We are currently building up the new lab "Direct Lineage Reprogramming and Brain Repair" at the Stem Cell and Brain Research Institute (SBRI, INSERM U1208) in Lyon. 

 

  • Sept 2017. Célia Lentini is awarded a PhD Fellowship by LFCE

Célia is awarded a competitive 4th year PhD Fellowship by the Ligue Française Contre l'Epilepsie (LFCE).  Congratulations to Célia !

http://www.lfce.fr/LES-LAUREATES-DES-BOURSES-2017_a698.html

 

  • July 2017. Week of experiments in the Berninger lab, Mainz, Germany. Lots of fun !

Recordings of induced neurons derived from astroglia reprogramming in the epileptic brain by Nicolas Marichal. Congrats Nico ! 

 

  • July 2017. Seminar by Célia Lentini at Institute of Physiological Chemistry, Medical Center of the Johannes Gutenberg University, Mainz, Germany

Invited by: Benedikt Berninger

 

  • May 2017. Symposium on "Direct Lineage Reprogramming for Brain Repair" organized by Christophe at the NeuroFrance Meeting, Bordeaux, France

One of the first Symposium on Direct Lineage Reprogramming in France bringing together Christophe Heinrich (SBRI, Lyon, France), Sophie Jarriault (IGBMC, Strasbourg, France), Caroline Rouaux (INSERM U1118, Strasbourg, France), Sergio Gascon (Institute of Stem Cell Research, Munich, Germany) and Bibal El Waly (IBDM, Marseille, France). 

Thanks to Sophie, Caroline, Bilal and Sergio who kindly accepted to present their data and contributed to this great program! 

https://www.neurosciences.asso.fr/V2/colloques/SN17/

 

  • May 2017. Seminar by Christophe at NeuroFrance Meeting, Bordeaux, France

Title:  Reprogramming of glial cells into functional neurons: A new avenue towards brain repair

https://scac.ada.wats-on.co.uk/Congress.aspx

 

  • April 2017. Rory Vignoles starts his PhD in the lab

Welcome Rory ! Rory has completed a Master Degree in Neuroscience with Distinction at Trinity College Dublin, the University of Dublin, Ireland. 

He did his Master thesis in the lab of Prof. Veronica Campbell and studied  "GPR55 signalling and receptor-mediated actions on neuronamolecular and cellular biology at Joseph Fourier University l viability and microglia function, in an in vitro model of Alzheimer’s Disease". 

 

                                                                                             2016

  • Dec 2016. Christophe is awarded the Attraction Package from the LabEx CORTEX, Lyon, France

Christophe is selected through a competitive international selection process as the laureate of the Laboratory of Excellence (LabEx) CORTEX Attraction Package.

He will move his lab to Lyon in June 2017 and will further develop his research program at the Stem Cell and Brain Research Institute (SBRI, INSERM U1208).

https://www.labex-cortex.com/en

 

  • Nov 2016. Seminar by Christophe at the 2nd International Conference on Stem Cells and Cancer, Lyon, France

Title:  Direct reprogramming of glial cells into functional neurons: A new avenue towards brain repair.

Session 3: Reprogramming/Tissue engineering

https://scac.ada.wats-on.co.uk/Congress.aspx

 

  • Aug 2016. Seminar by Marcos Romualdo Costa at Grenoble Institute of Neuroscience, Grenoble, France

Prof. Marcos Romualdo Costa from Brain Institute, Natal, Brazil

Title: Direct lineage-reprogramming of astrocytes into distinct subtypes in vitro and in vivo

Invited by: Christophe Heinrich

 

  • July 2016. Week of experiments in the Berninger lab in Mainz, Germany! Great time

Recordings of granule cells in the epileptic dendate gyrus by Nicolas Marichal. Congrats Nicolas !!

Célia Lentini is presenting her PhD results in the Berninger lab. 

https://fr-fr.facebook.com/BerningerLab/

 

  • May 2016. Seminar by Benedikt Berninger at Grenoble Institute of Neuroscience, Grenoble, France

Prof. Benedikt Berninger from Institute of Physiological Chemistry, Medical Center of the Johannes Gutenberg University, Mainz, Germany

Title: Reawakening the sleeping beauty in the adult brain: lineage conversion of brain-resident cells 

Invited by: Christophe Heinrich

 

  • March 2016. New publication from the Götz lab in Cell Stem Cell

Our friend Sergio Gascón is publishing a great story in Cell Stem Cell: Congrats to Sergio ! 

Gascón S, Murenu E, Masserdotti G, Ortega F, Russo GL, Petrik D, Deshpande A, Heinrich C, Karow M, Robertson SP, Schroeder T, Beckers J, Irmler M, Berndt C, Angeli JP, Conrad M, Berninger B and Götz M.

Identification and successful negotiation of a metabolic checkpoint in direct neuronal reprogramming. Cell Stem Cell, 2016, 18 (3): 396-409

http://www.sciencedirect.com.gate2.inist.fr/science/article/pii/S1934590915005482

 

  • Feb 2016. Christophe starts as a Junior Group Leader at Grenoble Institute of Neurosciences, INSERM U1216, Grenoble, France

Christophe is selected through a competitive selection process by the international Science Advisory Board of the Grenoble Institute of Neuroscience as a Junior Group Leader.

 

 

                                                                                             2015

 

  • June 2015. Seminar by Christophe at the ISSCR Annual Meeting (International Society for Stem Cell Research), Stockholm, Sweden

Title: Sox2-induced conversion of NG2 glia into neurons in the adult cerebral cortex following acute invasive injury.

CONCURRENT IIIC: TRANSDIFFERENTIATION AND REPROGRAMMING, VICTORIA HALL

http://www.isscr.org/meetings-events/annual-meetings/past-meetings/isscr-2015-stockholm

 

  • April 2015. Seminar by Benedikt Berninger at Grenoble Institute of Neuroscience, Grenoble, France

Prof. Benedikt Berninger from Institute of Physiological Chemistry, Medical Center of the Johannes Gutenberg University, Mainz, Germany

Title: Remodeling and reprogramming the adult brain 

Invited by: Christophe Heinrich

 

  • March 2015. Seminar by Christophe at Stem Cell and Brain Research Institute, Lyon, France

Title: Direct reprogramming of glial cells into functional neurons: A new avenue towards brain repair.

Invited by: Olivier Raineteau

 

  • Feb 2015. New publication from Christophe in Nature Cell Biology

Heinrich C, Spagnoli F and Berninger B.

In vivo reprogramming for tissue repair. Nature Cell Biology, 2015, 17 (3): 204-211.

http://www.nature.com/ncb/journal/v17/n3/full/ncb3108.html

 

  • Jan 2015. New publication from Christophe in Medecine & Sciences

Heinrich C and Rouaux C.

Inducing brain regeneration from within: in vivo reprogramming of endogenous somatic cells into neurons. Médecine et Sciences (Paris), 2015, 31 (1): 35-42

https://www-medecinesciences-org.gate2.inist.fr/fr/articles/medsci/abs/2015/01/medsci20153101p35/medsci20153101p35.html

 

                                                                                             2014

  • Nov 2014. New publication from Christophe in Stem Cell Reports

Heinrich C, Bergami M, Gascón S, Lepier A, Viganò F, Dimou L, Sutor B, Berninger B and Götz M. 

Sox2-mediated conversion of NG2 glia into induced neurons in the injured adult cerebral cortex. Stem Cell Reports, 2014, 3 (6): 1000-14

http://www.cell.com/stem-cell-reports/abstract/S2213-6711(14)00329-4

 

  • Oct 2014. Célia Lentini is joining the lab as a PhD student

Célia has completed her Masters in Neuroscience at the Joseph Fourier University of Grenoble and starts her PhD in the lab. 

 

  • Sept 2014. Seminar by Christophe at Collège de France, Paris, France

Title: Direct reprogramming of glial cells into functional neurons: A new avenue towards brain repair

Invited by: Nathalie Rouach

 

  • Sept 2014. Summer school of the NEURINOX consortium (European FP7), Athens, Greece

 

  • July 2014. Seminar by Christophe at Institute of Physiological Chemistry, Medical Center of the Johannes Gutenberg University, Mainz, Germany

Title: Sox2−mediated conversion of NG2 glia into induced neurons in the injured adult cerebral cortex

Invited by: Benedikt Berninger

 

  • July 2014. Christophe's research program is selected for funding by Agence Nationale de la Recherche (ANR)

Christophe is the recipient of an ANR Young Researchers (JCJC) to support his research. The JCJC  funding instrument allows young researchers to explore their own theme area, to assemble or  consolidate a team. 

 

  • Jan 2014. Célia Lentini is joining the lab as a Master student

Welcome Célia ! After completing a Degree in Molecular and Cellular Biology at the Joseph Fourier University of Grenoble, Célia joins the lab for her Master thesis. 

 

                                                                                             2013

  • Aug 2013. Christophe Heinrich is awarded the CURE Innovator Award

Christophe submitted his first grant as a PI to Citizens United for Research in Epilepsy (CURE), an American nongovernmental agency committed to funding cutting-edge research in epilepsy. Christophe receives the 2013 Innovator Award.

 https://www.cureepilepsy.org/our-research/grants-awarded/conversion-of-reactive