She earned her PhD in Paris, in 2001, and then worked as a post-doc at the Roslin Institute (Scotland). She joined INRA in 2003, at Jouy-en-Josas, to develop studies on chromatin remodeling during preimplantation development , mainly in murine and rabbit/bovine species. She is very experienced in the analysis of epigenetic reprogramming by powerful image analysis tools. Since her arrival at SBRI her project is to study chromatin & epigenetic reprogramming to totipotency. Model systems include embryos upon fertilization or nuclear transfer (cloning) as well as after pluripotency induction in somatic cells (iPSC) of various mammalian species.
|2017||24:106-117||Reprogramming of rabbit induced pluripotent stem cells toward epiblast and chimeric competency using Krüppel-like factors||Tapponnier Y, Afanassieff M, Aksoy I, Aubry M, Moulin A, Medjani L, Bouchereau W, Osteil P, Nurse-Francis J, Oikonomakos I, Joly T, Jouneau L, Archilla C, Schmaltz-Panneau B, Peynot N, Barasc H, Pinton A, Lecardonnel J, Gocza E, Beaujean N, Duranthon V, Savatier P||Stem Cell Res||-|
|2017||154(6):807-814||Embryo cell allocation patterns are not altered by biopsy but can be linked with further development||Sepulveda-Rincon LP, Islam N, Marsters P, Campbell BK, Beaujean N, Maalouf WE||Reproduction||-|
|2017||65(5):873-884||Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways||Jullien J, Vodnala M, Pasque V, Oikawa M, Miyamoto K, Allen G, David SA, Brochard V, Wang S, Bradshaw C, Koseki H, Sartorelli V, Beaujean N, Gurdon J||Mol Cell||-|
|2016||94(4):95||Three-Dimensional Distribution of UBF and Nopp140 in Relationship to Ribosomal DNA Transcription During Mouse Preimplantation Development||Koné MC, Fleurot R, Chebrout M, Debey P, Beaujean N, Bonnet-Garnier A||Biol Reprod||-|
|2016||95(6):123||Random Allocation of Blastomere Descendants to the Trophectoderm and ICM of the Bovine Blastocyst||Sepulveda-Rincon LP, Dube D, Adenot P, Laffont L, Ruffini S, Gall L, Campbell BK, Duranthon V, Beaujean N, Maalouf WE||Biol Reprod||-|
|2016||31(11):2471-2483||Assessment of 'one-step' versus 'sequential' embryo culture conditions through embryonic genome methylation and hydroxymethylation changes||Salvaing J, Peynot N, Bedhane MN, Veniel S, Pellier E, Boulesteix C, Beaujean N, Daniel N, Duranthon V||Hum Reprod||-|