Alumni team "Chronobiology and affective disorders"
My PhD project focuses on understanding how the mammalian retinal clock is entrained by light. I aim first to explore the molecular mechanisms underlying light entrainment of the retinal clock, especially the role of dopamine and the relative contributions of the different photoreceptors in these processes. Second, I will determine whether the absence of specific photoreceptors contributes to retinal clock dysfunction. Several complementary approaches are used including in vitro bioluminescence gene imaging, laser microdissection, RT-qPCR and monochromatic light stimulation.
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Reference | Title | Authors | Journal | PUB MED | ||
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2021 | S0166-2236(21)00237-X | Ocular and extraocular roles of neuropsin in vertebrates | Hugo Calligaro, Ouria Dkhissi-Benyahya, Satchidananda Panda | Trends Neurosci | - | ||
2020 | 26:106-116 | A standardized method to assess the endogenous activity and the light-response of the retinal clock in mammals | H Calligaro, C Kinane, M Bennis, C Coutanson, O Dkhissi-Benyahya | Mol Vis | - | ||