I obtained my Ph.D. degree from the University of Grenoble (France) in 1997; my research focused on axonal guidance, using chick skin sensory innervation during development as a model. I then spent the next 3,5 years as a post-doc (Shriver Center for Mental Retardation ; University of Massachusetts, Medical School (Waltham, Massachusetts, U.S.A)). I was still working on axonal guidance, using this time the rodent olfactory system as a model.
I came back to France in 2001, first as a postdoc and then as an assistant professor (Maître de conférences) in Patrick Mehlen's laboratory in Lyon (current name: Apoptosis, Cancer and Development; CRCL) where I studied the role of dependance during the development of the rodent nervous system.
I also worked in the CRNL, and in CARMEN before joining the SBRI.
I am an assistant professor of Genetics/Genomics/Developmental Biology at the Lyon1 University (Science and Technology; Biosciences Department). I am responsible of a Genomics teaching unit at Lyon1 University and of Neurophysiology practicla works at the ENS de Lyon.
In collaboration with Serge Nataf, PU-PH at the Lyon-1 university, I am using bioinformatics and data mining approaches to investigate the impact of immunity on cognition.
A current focus of interest is to assess the role of physiological autoimmunity on the development and maintenance of cognitive functions.
3A- Building the cerebral cortex: Cell and molecular mechanisms
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Reference | Title | Authors | Journal | PUB MED | ||
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2019 | 10:2704 | Common Neurodegeneration-Associated Proteins Are Physiologically Expressed by Human B Lymphocytes and Are Interconnected via the Inflammation/Autophagy-Related Proteins TRAF6 and SQSTM1 | Serge Nataf, Marine Guillen, Laurent Pays | Front Immunol | - | ||
2016 | 60(12):2691-2699 | Fructose overfeeding in first-degree relatives of type 2 diabetic patients impacts energy metabolism and mitochondrial functions in skeletal muscle | Kevin Seyssel, Emmanuelle Meugnier, Kim-Anne Lê, Christine Durand, Emmanuel Disse, Emilie Blond, Laurent Pays, Serge Nataf, John Brozek, Hubert Vidal, Luc Tappy, Martine Laville | Mol Nutr Food Res | - | ||
2002 | 417(6887):443-7 | Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation | Christelle Forcet, Elke Stein, Laurent Pays, Véronique Corset, Fabien Llambi, Marc Tessier-Lavigne, Patrick Mehlen | Nature | - | ||
2000 | 43(2):173-85 | Gal-NCAM is a differentially expressed marker for mature sensory neurons in the rat olfactory system | L Pays, G Schwarting | J Neurobiol | - | ||
1997 | 195(5):457-66 | Close link between cutaneous nerve pattern development and feather morphogenesis demonstrated by experimental production of neo-apteria and ectopic feathers: implication of chondroitin sulphate proteoglycans and other matrix molecules | L Pays, I Charvet, F J Hemming, R Saxod | Anat Embryol (Berl) | - | ||