Discover the
SBRI member :

Nasser Haddjeri


Research interests

Since 20 years, my research focuses on the neurobiology of mood disorders and their responses to antidepressant treatments. A main goal is to understand the neural bases associated to the antidepressant responses in order to develop novel therapeutics for affective disorders. My work particularly focus on gaining a clearer understanding of the physiology and pharmacology of brain monoamine neurotransmitters and how these neurotransmitter systems are affected by established and novel antidepressant strategies. To this end, I utilize a wide range of techniques including in vivo electrophysiology, behavioural analysis and immunocytochemistry.

Chronobiology and affective disorders
2023Sarah Delcourte, Amel Bouloufa, Renaud Rovera, Cécile Bétry, Erika Abrial, Ouria Dkhissi-Benyahya, Christophe Heinrich, Guillaume Marcy, Olivier Raineteau , Nasser Haddjeri, Guillaume Lucas, Adeline EtiévantChemogenetic activation of prefrontal astroglia enhances recognition memory performance in ratBiomed Pharmacother
2023 Chaimaa Kinane , Hugo Calligaro, Antonin Jandot, Christine Coutanson, Nasser Haddjeri, Mohamed Bennis, Ouria Dkhissi-BenyahyaDopamine modulates the retinal clock through melanopsin-dependent regulation of cholinergic waves during developmentBMC Biol
2022Manfredi-Lozano M, Leysen V, Adamo M, Paiva I, Rovera R, Pignat JM, Timzoura FE, Candlish M, Eddarkaoui S, Malone SA, Silva MSB, Trova S, Imbernon M, Decoster L, Cotellessa L, Tena-Sempere M, Claret M, Paoloni-Giacobino A, Plassard D, Paccou E, Vionnet N, Acierno J, Maceski AM, Lutti A, Pfrieger F, Rasika S, Santoni F, Boehm U, Ciofi P, Buée L, Haddjeri N, Boutillier AL, Kuhle J, Messina A, Draganski B, Giacobini P, Pitteloud N, Prevot VGnRH replacement rescues cognition in Down syndromeScience
2021Sébastien Bullich, Sarah Delcourte, Nasser Haddjeri, Bruno P GuiardLearned Immobility Produces Enduring Impairment of the HPA Axis Reactivity in Mice without Replicating the Broad Spectrum of Depressive-Like PhenotypeInt J Mol Sci
2021Delcourte S, Etievant A, Haddjeri NRole of central serotonin and noradrenaline interactions in the antidepressants’ action: Electrophysiological and neurochemical evidenceProgress in Brain Research
2020Etievant A, Haddjeri N, Lau TAntidepressants: Molecular Aspects of SSRIsNeuroPsychopharmacotherapy
2020Benjamin Portal, Sarah Delcourte, Renaud Rovera, Camille Lejards, Sebastien Bullich, Cécile E Malnou, Nasser Haddjeri, Nicole Déglon, Bruno P GuiardGenetic and pharmacological inactivation of astroglial connexin 43 differentially influences the acute response of antidepressant and anxiolytic drugsActa Physiol (Oxf)
2019Adeline Etievant, Thorsten Lau, Guillaume Lucas, Nasser HaddjeriSerotonin Neuronal Function from the Bed to the Bench: Is This Really a Mirrored Way?eNeuro
2019Calligaro H, Coutanson C, Najjar RP, Mazzaro N, Cooper HM, Haddjeri N, Felder-Schmittbuhl MP, Dkhissi-Benyahya ORods contribute to the light-induced phase shift of the retinal clock in mammalsPLoS Biol
2018Delcourte S, Ashby CR Jr, Rovera R, Kiss B, Adham N, Farkas B, Haddjeri NThe novel atypical antipsychotic cariprazine demonstrates dopamine D2 receptor-dependent partial agonist actions on rat mesencephalic dopamine neuronal activityCNS Neurosci Ther