Discover the
SBRI member :

Nathalie Beaujean
1728459111846b-2

DR2

Research interests

Dr. Beaujean is a Research Director at French National Institute for Agriculture, Food, and Environment (INRAE) with a long career in epigenetics, chromatin biology, reprogramming and stem cell biology. Her work focuses on epigenetic reprogramming of embryos and pluripotent stem cells across mammalian species, exploiting transcriptomic, epigenetic and metabolic approaches to understand totipotency and pluripotency in early development.

Her expertise includes:

  • Epigenetics and chromatin regulation
  • Induced pluripotency and nuclear reprogramming
  • Embryonic stem cell biology and totipotency
  • Molecular and cellular biology of mammalian embryos

 

2
Pluripotent stem cells in mammals
live-imaging

Live Imaging

YearAuthorsTitleJournalPubMedPDF
2024Nathalie BeaujeanDefining the chromatin signature of pluripotencyNat Cell Biol
2022Wilhelm Bouchereau, Luc Jouneau, Catherine Archilla, Irène Aksoy, Anais Moulin, Nathalie Daniel, Nathalie Peynot, Sophie Calderari, Thierry Joly, Murielle Godet, Yan Jaszczyszyn, Marine Pratlong, Dany Severac, Pierre Savatier, Véronique Duranthon, Marielle Afanassieff, Nathalie BeaujeanMajor transcriptomic, epigenetic and metabolic changes underlie the pluripotency continuum in rabbit preimplantation embryosDevelopment
2022Chebrout M, Koné MC, Jan HU, Cournut M, Letheule M, Fleurot R, Aguirre-Lavin T, Peynot N, Jouneau A, Beaujean N, Bonnet-Garnier ATranscription of rRNA in early mouse embryos promotes chromatin reorganization and expression of major satellite repeatsJ Cell Sci
2021Brochard V, Beaujean NSomatic Reprograming by Nuclear TransferMethods Mol Biol
2020Adam Burton, Vincent Brochard, Carmen Galan, Elias R Ruiz-Morales, Quirze Rovira, Diego Rodriguez-Terrones, Kai Kruse, Stéphanie Le Gras, Vishnu S Udayakumar, Hang Gyeong Chin, André Eid, Xiaoyu Liu, Chenfei Wang, Shaorong Gao, Sriharsa Pradhan, Juan M Vaquerizas, Nathalie Beaujean, Thomas Jenuwein, Maria-Elena Torres-PadillaHeterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3Nat Cell Biol
2020Marielle Afanassieff, Florence Perold, Wilhelm Bouchereau, Antoine Cadiou, Nathalie BeaujeanEmbryo-derived and induced pluripotent stem cells: Towards naive pluripotency and chimeric competency in rabbits Exp Cell Res
2019Camargo LSA, Aguirre-Lavin T, Adenot P, Araujo TD, Mendes VRA, Louro ID, Beaujean N, Souza EDHeat shock during in vitro maturation induces chromatin modifications in the bovine embryoReproduction
2018Bonnet-Garnier A, Kiêu K, Aguirre-Lavin T, Tar K, Flores P, Liu Z, Peynot N, Chebrout M, Dinnyés A, Duranthon V, Beaujean NThree-dimensional analysis of nuclear heterochromatin distribution during early development in the rabbitChromosoma
2018Afanassieff M, Aksoy I, Beaujean N, Bourillot PY, Savatier PFifty shades of pluripotencyMed Sci (Paris)
2018Beaujean N, Salvaing J, Hadi NAA, Pennings SAntibody-Based Detection of Global Nuclear DNA Methylation in Cells, Tissue Sections, and Mammalian EmbryosMethods Mol Biol