DR2
After a Ph.D. (2001) in Developmental Biology on the Pierre-et-Marie Currie Campus in Paris, I worked as a Post-Doc at the Roslin Institute with Prof. Ian WILMUT (Scotland). I joined the French National Institute of Agronomic Research in 2003, to develop studies on chromatin remodeling during embryonic development, upon fertilization or cloning (by somatic cell nuclear transfer, SCNT). Since 2016, I supervise projects on epigenetic reprogramming at the Stem Cell & Brain Research Institute (SBRI), in Lyon. My expertise mostly relies on embryo micromanipulations (IVF, ICSI, SCNT, chimerism), pluripotent stem cells (ESC, iPSC) & the use/development of image analysis tools, in murine and rabbit species.
Year | Authors | Title | Journal | PubMed | |
---|---|---|---|---|---|
2024 | Nathalie Beaujean | Defining the chromatin signature of pluripotency | Nat Cell Biol | ||
2022 | Wilhelm Bouchereau, Luc Jouneau, Catherine Archilla, Irène Aksoy, Anais Moulin, Nathalie Daniel, Nathalie Peynot, Sophie Calderari, Thierry Joly, Murielle Godet, Yan Jaszczyszyn, Marine Pratlong, Dany Severac, Pierre Savatier, Véronique Duranthon, Marielle Afanassieff, Nathalie Beaujean | Major transcriptomic, epigenetic and metabolic changes underlie the pluripotency continuum in rabbit preimplantation embryos | Development | ||
2022 | Chebrout M, Koné MC, Jan HU, Cournut M, Letheule M, Fleurot R, Aguirre-Lavin T, Peynot N, Jouneau A, Beaujean N, Bonnet-Garnier A | Transcription of rRNA in early mouse embryos promotes chromatin reorganization and expression of major satellite repeats | J Cell Sci | ||
2021 | Brochard V, Beaujean N | Somatic Reprograming by Nuclear Transfer | Methods Mol Biol | ||
2020 | Adam Burton, Vincent Brochard, Carmen Galan, Elias R Ruiz-Morales, Quirze Rovira, Diego Rodriguez-Terrones, Kai Kruse, Stéphanie Le Gras, Vishnu S Udayakumar, Hang Gyeong Chin, André Eid, Xiaoyu Liu, Chenfei Wang, Shaorong Gao, Sriharsa Pradhan, Juan M Vaquerizas, Nathalie Beaujean, Thomas Jenuwein, Maria-Elena Torres-Padilla | Heterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3 | Nat Cell Biol | ||
2020 | Marielle Afanassieff, Florence Perold, Wilhelm Bouchereau, Antoine Cadiou, Nathalie Beaujean | Embryo-derived and induced pluripotent stem cells: Towards naive pluripotency and chimeric competency in rabbits | Exp Cell Res | ||
2019 | Camargo LSA, Aguirre-Lavin T, Adenot P, Araujo TD, Mendes VRA, Louro ID, Beaujean N, Souza ED | Heat shock during in vitro maturation induces chromatin modifications in the bovine embryo | Reproduction | ||
2018 | Beaujean N, Salvaing J, Hadi NAA, Pennings S | Antibody-Based Detection of Global Nuclear DNA Methylation in Cells, Tissue Sections, and Mammalian Embryos | Methods Mol Biol | ||
2018 | Tosolini M, Brochard V, Adenot P, Chebrout M, Grillo G, Navia V, Beaujean N, Francastel C, Bonnet-Garnier A, Jouneau A | Contrasting epigenetic states of heterochromatin in the different types of mouse pluripotent stem cells | Sci Rep | ||
2018 | Bonnet-Garnier A, Kiêu K, Aguirre-Lavin T, Tar K, Flores P, Liu Z, Peynot N, Chebrout M, Dinnyés A, Duranthon V, Beaujean N | Three-dimensional analysis of nuclear heterochromatin distribution during early development in the rabbit | Chromosoma |