Discover the
SBRI member :
Pierre-Yves Bourillot
CRCN
Research interests
He obtained his PhD from the University of Lyon in 1997. After a 3-year postdoc at the University of Cambridge (UK), he joined the Savatier team in 2000. He studies LIF/STAT3 signalling in mouse and human ES cells. In collaboration with Hongwei Chen, he reprogrammed human ES cells to ground-like state of pluripotency. He also studies the role of long non-coding RNAs in ground state pluripotency.
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18 avenue du Doyen Lépine
69500 Bron Cedex France
- 04 72 91 34 58
- pierre-yves.bourillot@inserm.fr
- Member of ...
- Selected publications of Pierre-Yves Bourillot
| Year | Authors | Title | Journal | PubMed | |
|---|---|---|---|---|---|
| 2021 | Aksoy I, Rognard C, Moulin A, Marcy G, Masfaraud E, Wianny F, Cortay V, Bellemin-Ménard A, Doerflinger N, Dirheimer M, Mayère C, Bourillot PY, Lynch C, Raineteau O, Joly T, Dehay C, Serrano M, Afanassieff M, Savatier P | Apoptosis, G1 Phase Stall, and Premature Differentiation Account for Low Chimeric Competence of Human and Rhesus Monkey Naive Pluripotent Stem Cells | Stem Cell Reports | ||
| 2020 | Bourillot PY, Santamaria C, David L, Savatier P | GP130 signaling and the control of naïve pluripotency in humans, monkeys, and pigs | Exp Cell Res | ||
| 2019 | Gonnot F, Langer D, Bourillot PY, Doerflinger N, Savatier P | Regulation of Cyclin E by transcription factors of the naïve pluripotency network in mouse embryonic stem cells | Cell Cycle | ||
| 2018 | Afanassieff M, Aksoy I, Beaujean N, Bourillot PY, Savatier P | Fifty shades of pluripotency | Med Sci (Paris) | ||
| 2016 | Wianny F, Blachère T, Godet M, Guillermas R, Cortay V, Bourillot PY, Lefèvre A, Savatier P, Dehay C | Epigenetic status of H19/IGF2 and SNRPN imprinted genes in aborted and successfully derived embryonic stem cell lines in non-human primates | Stem Cell Res | ||
| 2015 | Chen H, Aksoy I, Gonnot F, Osteil P, Aubry M, Hamela C, Rognard C, Hochard A, Voisin S, Fontaine E, Mure M, Afanassieff M, Cleroux E, Guibert S, Chen J, Vallot C, Acloque H, Genthon C, Donnadieu C, De Vos J, Sanlaville D, Guérin JF, Weber M, Stanton LW, Rougeulle C, Pain B, Bourillot PY, Savatier P | Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency | Nat Commun | ||
| 2014 | Aksoy I, Giudice V, Delahaye E, Wianny F, Aubry M, Mure M, Chen J, Jauch R, Bogu GK, Nolden T, Himmelbauer H, Xavier Doss M, Sachinidis A, Schulz H, Hummel O, Martinelli P, Hübner N, Stanton LW, Real FX, Bourillot PY, Savatier P | Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells | Nat Commun | ||
| 2013 | Coronado D, Godet M, Bourillot PY, Tapponnier Y, Bernat A, Petit M, Afanassieff M, Markossian S, Malashicheva A, Iacone R, Anastassiadis K, Savatier P | A short G1 phase is an intrinsic determinant of naïve embryonic stem cell pluripotency | Stem Cell Res | ||
| 2011 | Wianny F, Bourillot PY, Dehay C | Embryonic stem cells in non-human primates: An overview of neural differentiation potential | Differentiation | ||
| 2010 | Bourillot PY, Savatier P | Krüppel-like transcription factors and control of pluripotency | BMC Biol |