Discover the
SBRI member :
Irene Aksoy
CRCN
Research interests
She obtained her PhD from the University of Lyon in 2008. After a 5-year postdoc at the Genome Institute of Singapore, where she studied different aspects of somatic cell reprogramming, she joined the Savatier team in 2013 to work on pluripotency in non-human primates. She studies the transcriptome of the macaque pre-implantation, and reprograms ES cell lines suitable for the generation of somatic chimaeras in the rhesus macaque.
-
18 avenue du Doyen Lépine
69500 Bron Cedex France
- 04 72 91 34 58
- irene.aksoy@inserm.fr
- Member of ...
- Selected publications of Irene Aksoy
| Year | Authors | Title | Journal | PubMed | |
|---|---|---|---|---|---|
| 2023 | Preeyanan Anwised, Ratree Moorawong, Worawalan Samruan, Sirilak Somredngan, Jittanun Srisutush, Chuti Laowtammathron, Irene Aksoy, Rangsun Parnpai, Pierre Savatier | An expedition in the jungle of pluripotent stem cells of non-human primates | Stem Cell Reports | ||
| 2022 | Wilhelm Bouchereau, Luc Jouneau, Catherine Archilla, Irène Aksoy, Anais Moulin, Nathalie Daniel, Nathalie Peynot, Sophie Calderari, Thierry Joly, Murielle Godet, Yan Jaszczyszyn, Marine Pratlong, Dany Severac, Pierre Savatier, Véronique Duranthon, Marielle Afanassieff, Nathalie Beaujean | Major transcriptomic, epigenetic and metabolic changes underlie the pluripotency continuum in rabbit preimplantation embryos | Development | ||
| 2022 | Fadlullah MZH, Neo WH, Lie-A-Ling M, Thambyrajah R, Patel R, Mevel R, Aksoy I, Do Khoa N, Savatier P, Fontenille L, Baker SM, Rattray M, Kouskoff V, Lacaud G | Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE | Blood | ||
| 2021 | Savatier P, Aksoy I | Interspecies systemic chimeras | Med Sci (Paris) | ||
| 2021 | Aksoy I, Rognard C, Moulin A, Marcy G, Masfaraud E, Wianny F, Cortay V, Bellemin-Ménard A, Doerflinger N, Dirheimer M, Mayère C, Bourillot PY, Lynch C, Raineteau O, Joly T, Dehay C, Serrano M, Afanassieff M, Savatier P | Apoptosis, G1 Phase Stall, and Premature Differentiation Account for Low Chimeric Competence of Human and Rhesus Monkey Naive Pluripotent Stem Cells | Stem Cell Reports | ||
| 2020 | Lynch CJ, Bernad R, Martínez-Val A, Shahbazi MN, Nóbrega-Pereira S, Calvo I, Blanco-Aparicio C, Tarantino C, Garreta E, Richart-Ginés L, Alcazar N, Graña-Castro O, Gómez-Lopez G, Aksoy I, Muñoz-Martín M, Martinez S, Ortega S, Prieto S, Simboeck E, Camasses A, Stephan-Otto Attolini C, Fernandez AF, Sierra MI, Fraga MF, Pastor J, Fisher D, Montserrat N, Savatier P, Muñoz J, Zernicka-Goetz M, Serrano M | Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases | Nat Cell Biol | ||
| 2018 | Afanassieff M, Aksoy I, Beaujean N, Bourillot PY, Savatier P | Fifty shades of pluripotency | Med Sci (Paris) | ||
| 2017 | Aksoy I, Utami KH, Winata CL, Hilmer AM, Rouam SL, Briault S, Davila S, Stanton LW, Cacheux V | Personalized genome sequencing coupled with iPSC technology identifies GTDC1 as a gene involved in neurodevelopmental disorders | Hum Mol Genet | ||
| 2017 | Tapponnier Y, Afanassieff M, Aksoy I, Aubry M, Moulin A, Medjani L, Bouchereau W, Osteil P, Nurse-Francis J, Oikonomakos I, Joly T, Jouneau L, Archilla C, Schmaltz-Panneau B, Peynot N, Barasc H, Pinton A, Lecardonnel J, Gocza E, Beaujean N, Duranthon V, Savatier P | Reprogramming of rabbit induced pluripotent stem cells toward epiblast and chimeric competency using Krüppel-like factors | Stem Cell Res |