SBRI
Stem-cell & Brain
Research Institute

From life to intelligence

Welcome to SBRI​

The Stem cell and Brain Research Institute (SBRI) was created in 2007 by Henry Kennedy and in 2011, renewed under the directorship of Colette Dehay, with Henry Kennedy as deputy director. SBRI is affiliated to INSERM and University de Lyon with strong links to INRA and CNRS.

SBRI research is multidisciplinary with interests ranging from stem cells biology, developmental neurobiologyintegrative and cognitive neuroscience and chronobiology disorders.

One common asset is the investigation of human and non-human primate specific features addressed at multiple levels of exploration ranging from the earliest embryonic developmental stages to the structure and function observed in the adult cortex.

Meet the SBRI
research teams

The 103 research staff at SBRI are organized in 6 teams and 1 clinical/translational research platform (StemGamE). The main research axes are stem cell biology, and integrative and cognitive neuroscience.

There are strong continuities between teams, which not only share technical approaches, but also common scientific objectives. SBRI brings together cutting-edge experimental techniques and advanced technology to seek out an in-depth understanding of primate specific features at the molecular, cell and system level.

1
Physiology and biotechnology of Embryonic stem cells
2
Pluripotent stem cells in mammals
3A
Building the cerebral cortex: Cell and molecular mechanisms
3B
Building the cerebral cortex: Connectomics
4A
Cellular reprogramming in the brain
4B
Cellular programming in the brain
5
Neurobiology of executive functions
6
Chronobiology and affective disorders
Conference by Fausto Carauna
December 2, 2022 - 2:00 pm
Flexibilité du comportement chez le primate : étude des dynamiques et connectivités fonctionnelles frontales
March 25, 2022 - 2:00 pm
Interview and commentaries about Nils Kolling's new publication in PlosBiol
April 8, 2022 - 9:45 am

Scientific excellency

The quality of SBRI activities has been acknowledged by excellent levels of international (UE, HFSP) funding as well as by PALSE/IdeX start-up grants.

The recently awarded funds from “Investissements d’Avenir” INGESTEM program have significantly contributed to the improvement and development of SBRI infrastructure. SBRI teams are members of the “Laboratoire d’excellence (Labex)”entitled “CORTEX”, headed by Henry Kennedy, and of the “LabEX DEVweCAN”(headed by P. Mehlen and bringing together teams in developmental biology and cancer research).